Actin-Binding Proteins and Disease by Cris dos Remedios, Deepak Chhabra

By Cris dos Remedios, Deepak Chhabra

This quantity, written by means of specialists within the box, is the 1st to house the connection among human illness and the actin cytoskeleton. It presents overviews of actin and chosen actin-binding proteins, after which makes a speciality of ailments that contain those proteins. particular chapters care for actin, cofilin, profilin, gelsolin and thymosin ¾4. different chapters talk about the jobs of a number of actin-binding proteins in melanoma and metastasis, leukocyte problems, and center failure, and there's a bankruptcy that describes how intracellular pathogens use the host actin cytoskeleton. This seminal quantity is meant for researchers, clinicians, physicians, and graduate scholars within the fields of biochemistry, cellphone biology, microbiology, immunology, and genetics.

Show description

Read Online or Download Actin-Binding Proteins and Disease PDF

Similar molecular biology books

Systems Biology in Biotech & Pharma: A Changing Paradigm (SpringerBriefs in Pharmaceutical Science & Drug Development)

The USA is at present good prior to the remainder of the realm within the improvement and alertness of SB and its ideas particularly as they pertain to easy clinical learn and improvement.  This lead is basically as a result of its past begin within the educational area. even though, there's proof of fast improvement in either the UK/EU and Japan, and the space is narrowing, really within the united kingdom.

Epigenetics

The significance of epigenetic rules of gene expression, relatively in larger organisms, is now transparent and the 2004 chilly Spring Harbor Annual Symposium supplied many new examples in addition to insights into the underlying mechanisms. The ensuing quantity with over 60 papers from specialists around the box covers quite a few elements of nuclear association and dynamics; genomic imprinting, chromosomal inactivation, and different examples of gene silencing; the histone and DNA ameliorations linked to those stipulations; and the jobs of RNA and protein regulators in developing and preserving those states.

Biophysics For Dummies

The joys, effortless approach to wake up to hurry on biophysics techniques, ideas, and practices essentially the most different of recent clinical disciplines, biophysics applies equipment and applied sciences from physics to the research of organic platforms and phenomena, from the human anxious process to soil erosion to international warming.

The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site Specific Genome Alterations,

This new quantity of tools in Enzymology maintains the legacy of this most effective serial with caliber chapters authored by way of leaders within the box. This quantity covers fresh examine and strategies improvement for altering the DNA series in the genomes of cells and organisms. targeting enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular instruments to introduce or delete genetic details at particular websites within the genomes of animal, plant and bacterial cells.

Extra info for Actin-Binding Proteins and Disease

Example text

H. 1973. Congenital fiber type disproportion. In Clinical Studies in Myology. International Congress Series No. 295. B. A. Kakulas (Editor). Excerpta Medica, Amsterdam. pp. 147–159. , Knight, P. , Sparrow, J. , Holt, J. and Trinick, J. 2004. Structural studies of arthrin: Monoubiquitinated actin. J. Mol. Biol. 341, 1161–1173. , Cook, R. K. and Rubenstein, P. A. 1993. Yeast actin with a mutation in the hydrophobic plug between subdomain-3 and subdomain-4 (L(266)D) displays a cold-sensitive polymerization defect.

Mahadeo, D. and Cotter, D. A. 2000. Novel actin cytoskeleton: Actin tubules. Cell Struct. Funct. 25, 291–295. , Schankin, C. , Curwen, R. , Caves, L. S. , Fink, R. H. , Sparrow, J. , Mayhew, P. J. and Veigel, C. 2003. Molecular evolutionary convergence of the flight muscle protein arthrin in Diptera and Hemiptera. Mol. Biol. Evol. 20, 2019–2033. Schröder, J. , Durling, H. and Laing, N. G. 2004. Actin myopathy with nemaline bodies, intranuclear rods and a heterozygous mutations in ACTA1 (Asp154Asn).

Mayhew, P. J. and Veigel, C. 2003. Molecular evolutionary convergence of the flight muscle protein arthrin in Diptera and Hemiptera. Mol. Biol. Evol. 20, 2019–2033. Schröder, J. , Durling, H. and Laing, N. G. 2004. Actin myopathy with nemaline bodies, intranuclear rods and a heterozygous mutations in ACTA1 (Asp154Asn). Acta Neuropathol. 108, 250–256. , Clemen, C. , Hayashi, Y. , Arahata, K. and Carpen, O. 2003. Beyond LGMD1A: Myotilin is a component of central core lesions and nemaline rods. Neuromuscul.

Download PDF sample

Rated 4.26 of 5 – based on 29 votes